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Rabbit Anti-Opticin/Cy5 Conjugated antibody (bs-19647R-Cy5)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-19647R-Cy5
英文名稱 Rabbit Anti-Opticin/Cy5 Conjugated antibody
中文名稱 Cy5標記的Opticin蛋白抗體
別    名 Oculoglycan; OPT; OPT_HUMAN; OPTC; Opticin.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  神經生物學  信號轉導  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Guinea Pig, Cat, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 37kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Opticin
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
Opticin belongs to class III of the small leucine-rich repeat protein (SLRP) family. Members of this family are typically associated with the extracellular matrix. Opticin is present in significant quantities in the vitreous of the eye and also localizes to the cornea, iris, ciliary body, optic nerve, choroid, retina, and fetal liver. Opticin may noncovalently bind collagen fibrils and regulate fibril morphology, spacing, and organization. The opticin gene is mapped to a region of chromosome 1 that is associated with the inherited eye diseases age-related macular degeneration (AMD) and posterior column ataxia with retinosa pigmentosa (AXPC1). [provided by RefSeq, Jul 2008]

Function:
Binds collagen fibrils.

Subcellular Location:
Secreted > extracellular space > extracellular matrix.Entrez Gene: 26254 Human Entrez Gene: 269120 Mouse Entrez Gene: 304802 Rat Omim: 605127 Human SwissProt: Q9UBM4 Human SwissProt: Q920A0 Mouse Unigene: 632468 Human Unigene: 59985 Mouse

Tissue Specificity:
Retina, iris, ligament, skin and fetal liver.

Post-translational modifications:
O-glycosylated.

Similarity:
Belongs to the small leucine-rich proteoglycan (SLRP) family.
SLRP class III subfamily.
Contains 6 LRR (leucine-rich) repeats.
Contains 1 LRRNT domain.

Database links:

Entrez Gene: 26254 Human

Entrez Gene: 269120 Mouse

Entrez Gene: 304802 Rat

Omim: 605127 Human

SwissProt: Q9UBM4 Human

SwissProt: Q920A0 Mouse

Unigene: 632468 Human

Unigene: 59985 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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