| 產品編號 | bs-0315R-Gold |
| 英文名稱 | Rabbit Anti-FGL2/Gold Conjugated antibody |
| 中文名稱 | 膠體金標記的凝血酶原酶/纖維蛋白原2抗體 |
| 別 名 | Fibroleukin; Cytotoxic T-lymphocyte-specific protein; Fibrinogen-like protein 2; Fibrinogen like protein 2; Prothrombinase; Fibroleukin; pT49; T49; FGL2_HUMAN. |
| 規格價格 | 100ul/2980元 購買 大包裝/詢價 |
| 說 明 書 | 100ul（10nm 15nm 35nm） |
| 研究領域 | 免疫學 t-淋巴細胞 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應 | (predicted: Rat, ) |
| 產品應用 | IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 49kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 0.4mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from Rat FGL2 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲 存 液 | 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
| 保存條件 | Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles. |
| 產品介紹 |
background: FGL2 is a secreted protein that is similar to the beta- and gamma-chains of fibrinogen. The carboxyl-terminus of the encoded protein consists of the fibrinogen-related domains (FRED). The encoded protein forms a tetrameric complex which is stabilized by interchain disulfide bonds. It may play a role in physiologic functions at mucosal sites. It is constitutively expressed in cytotoxic T-cells. Lack of expression in other lymphoid- and nonlymphoid-derived cell lines suggested that expression of FGL2 may be restricted to lymphocytes. FGL2 is induced via a mechanism involving IFNG and components of the IFNG signaling pathway, including STAT1 and IRF1. Function: May play a role in physiologic lymphocyte functions at mucosal sites Subunit: Homotetramer; disulfide-linked. Subcellular Location: Secreted. Tissue Specificity: Constitutively expressed in cytotoxic T-cells. Similarity: Contains 1 fibrinogen C-terminal domain. Database links: Entrez Gene: 10875 Human Entrez Gene: 14190 Mouse Omim: 605351 Human SwissProt: Q14314 Human SwissProt: P12804 Mouse Unigene: 520989 Human Unigene: 292100 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. fgL-2蛋白是新近發現的一種凝血因子，它通過直接激活凝血酶原啟動凝血過程。一 系列實驗證明，該蛋白在肝細胞壞死中起到重要作用。對乙肝患者肝組織免疫組織化學染色hfg12在重型乙型肝炎患者高表達。 凝血酶原酶(簡稱fgl2)蛋白屬于纖維蛋白原家族的一員,由活化的巨噬細胞表達,具有凝血酶原酶的活力,能催化凝血酶原轉化為凝血酶,啟動凝血過程. |
| 1、抗體溶解方法 | |
| 2、抗體修復方式 | |
| 3、常用試劑的配制 | |
| 4、免疫組化操作步驟 | |
| 5、免疫組化問題解答 | |
| 6、Western Blotting 操作步驟 | |
| 7、Western Blotting 問題解答 | |
| 8、關于肽鏈的設計 | |
| 9、多肽的溶解與保存 | |
| 10、酶標抗體效價測定程序 | |
