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ZIC4 Rabbit pAb (bs-19238R)  
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產品編號 bs-19238R
英文名稱 ZIC4 Rabbit pAb
中文名稱 小腦鋅指ZIC4蛋白抗體
別    名 FLJ42609; FLJ45833; Zic family member 4; ZIC4; ZIC4_HUMAN; Zinc family member 4 protein HZIC4; Zinc finger protein of cerebellum 4; Zinc finger protein of the cerebellum 4; Zinc finger protein ZIC 4.  
Specific References  (1)     |     bs-19238R has been referenced in 1 publications.
[IF=2.456] Han W et al. Clinicopathologic and Prognostic Significance of the Zinc Finger of the Cerebellum Family in Invasive Breast Cancer.J Breast Cancer. 2018 Mar;21(1):51-61.  IHC ;  Human.  
研究領域 神經生物學  轉錄調節因子  鋅指蛋白  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應 Mouse (predicted: Human,Rat,Rabbit,Pig,Sheep,Cow,Dog,Horse)
產品應用 ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 37 kDa
檢測分子量
細胞定位 細胞核 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ZIC4: 231-334/334 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 This gene encodes a member of the ZIC family of C2H2-type zinc finger proteins. Members of this family are important during development, and have been associated with X-linked visceral heterotaxy and holoprosencephaly type 5. This gene is closely linked to the gene encoding zinc finger protein of the cerebellum 1, a related family member on chromosome 3. Heterozygous deletion of these linked genes is involved in Dandy-Walker malformation, which is a congenital cerebellar malformation. Multiple transcript variants have been identified for this gene. [provided by RefSeq, Dec 2009]

Function:
Binds to DNA.

Subcellular Location:
Nucleus.

Similarity:
Belongs to the GLI C2H2-type zinc-finger protein family.
Contains 5 C2H2-type zinc fingers.

SWISS:
Q8N9L1

Gene ID:
84107

Database links:

Entrez Gene: 84107 Human

Entrez Gene: 22774 Mouse

Entrez Gene: 315882 Rat

Omim: 608948 Human

SwissProt: Q8N9L1 Human

SwissProt: Q61467 Mouse

Unigene: 415766 Human

Unigene: 434835 Mouse

Unigene: 8062 Mouse



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