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DNER Rabbit pAb (bs-12115R)  
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產品編號 bs-12115R
英文名稱 DNER Rabbit pAb
中文名稱 腦表皮生長因子跨膜蛋白DNER抗體
別    名 Brain EGF repeat-containing transmembrane protein; Bret; delta and Notch-like epidermal growth factor-related receptor; delta/notch-like EGF-related receptor; Dner; DNER_HUMAN; PRO299; Transmembrane protein Bet; UNQ26.  
研究領域 神經生物學  信號轉導  干細胞  細胞表面分子  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human,Mouse,Rat,Sheep,Cow,Dog)
產品應用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 75 kDa
檢測分子量
細胞定位 細胞漿 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human DNER: 185-300/737 <Extracellular>
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 Activator of the NOTCH1 pathway. May mediate neuron-glia interaction during astrocytogenesis.

Function:
Activator of the NOTCH1 pathway. May mediate neuron-glia interaction during astrocytogenesis.

Subunit:
Interacts with AP1G1. Interacts with NOTCH1.

Subcellular Location:
Cell membrane. Present on the membrane of dendrites and cell bodies but excluded from axonal membrane. Also found in early endosomes in the somatodendritic region.

Tissue Specificity:
Expressed in brain, spinal cord and adrenal gland.

Similarity:
Contains 10 EGF-like domains.
Contains 1 follistatin-like domain.

SWISS:
Q8NFT8

Gene ID:
92737

Database links:

Entrez Gene: 92737 Human

Entrez Gene: 227325 Mouse

Entrez Gene: 316573 Rat

Omim: 607299 Human

SwissProt: Q8NFT8 Human

SwissProt: Q8JZM4 Mouse

Unigene: 234074 Human

Unigene: 292560 Mouse



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