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BPI Rabbit pAb (bs-9892R)  
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50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包裝/詢價
產品編號 bs-9892R
英文名稱 BPI Rabbit pAb
中文名稱 中性粒細胞殺菌蛋白BP30抗體
別    名 CAP57; Neutrophil Bactericidal Protein BP30; Bactericidal permeability-increasing protein; Bactericidal/permeability increasing protein; BPI_HUMAN; CAP 57; CAP-57; BPI fold containing family D, member 1; BPIFD1.  
研究領域 免疫學  微生物學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human)
產品應用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:50-200,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 51 kDa
檢測分子量
細胞定位 細胞漿 細胞膜 分泌型蛋白 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CAP57: 1-100/487 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 The cytotoxic action of BPI is limited to many species of Gram-negative bacteria; this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope. Has antibacterial activity against the Gram-nagative bacterium P.aeruginosa, this activity is inhibited by LPS from P.aeruginosa.

Function:
The cytotoxic action of BPI is limited to many species of Gram-negative bacteria; this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope. Has antibacterial activity against the Gram-nagative bacterium P.aeruginosa, this activity is inhibited by LPS from P.aeruginosa.

Subunit:
Monomer. Homodimer; disulfide-linked.

Subcellular Location:
Secreted. Cytoplasmic granule membrane. Membrane-associated in polymorphonuclear Leukocytes (PMN) granules.

Tissue Specificity:
Restricted to cells of the myeloid series.

Similarity:
Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.

SWISS:
P17213

Gene ID:
671

Database links:

Entrez Gene: 671 Human

Omim: 109195 Human

SwissProt: P17213 Human

Unigene: 529019 Human



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