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AMH Rabbit pAb (bs-4687R)  
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50ul/1180.00元
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產品編號 bs-4687R
英文名稱 AMH Rabbit pAb
中文名稱 Muellerian繆勒管激素抑制因子抗體
別    名 MIS_HUMAN; Anti muellerian hormone; MIF; MIS; Muellerian inhibiting factor; Mullerian inhibiting substance; Muellerian-inhibiting factor; Anti-Muellerian hormone; AMH; Muellerian-inhibiting substance.  
Specific References  (4)     |     bs-4687R has been referenced in 4 publications.
[IF=11.459] Su Zhouet al. Ovarian Dysfunction Induced by Chronic Whole‐Body PM2.5 Exposure. Small . 2020 Aug;16(33):e2000845.  ELISA ;  mouse.  
[IF=6.183] Shan Zhang. et al. Early evaluation of survival of the transplanted ovaries through ultrasound molecular imaging via targeted nanobubbles. Biomater Sci-Uk. 2020 Sep;8(19):5402-5414  WB,IF ;  Rat.  
[IF=4.384] Jiao-jiao ZHANG. et al. Cold plasma promotes Sertoli cell proliferation via AMPK-mTOR signaling pathway1. J INTEGR AGR. 2022 Jul;:  IF ;  Chicken.  
[IF=2.984] Wang W et al. Amh dominant expression in Sertoli cells during the testicular differentiation and development stages in the olive flounder Paralichthys olivaceus. Gene . 2020 Sep 10;755:144906.  IHC ;  flounder.  
研究領域 腫瘤  細胞生物  發育生物學  信號轉導  干細胞  生長因子和激素  轉錄調節因子  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human (predicted: Mouse,Rat,Pig,Cow,Dog,Horse)
產品應用 WB=1:500-2000,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 57 kDa
檢測分子量
細胞定位 分泌型蛋白 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human AMH: 501-560/560 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 Anti-Mullerian hormone is a member of the transforming growth factor-beta gene family which mediates male sexual differentiation. Anti-Mullerian hormone causes the regression of Mullerian ducts which would otherwise differentiate into the uterus and fallopian tubes. Some mutations in the anti-Mullerian hormone result in persistent Mullerian duct syndrome. [provided by RefSeq, Jul 2008].

Function:
This glycoprotein, produced by the Sertoli cells of the testis, causes regression of the Muellerian duct. It is also able to inhibit the growth of tumors derived from tissues of Muellerian duct origin.

Subunit:
Homodimer; disulfide-linked.

Subcellular Location:
Secreted.

DISEASE:
Persistent Muellerian duct syndrome 1 (PMDS1) [MIM:261550]: A form of male pseudohermaphroditism characterized by a failure of Muellerian duct regression in otherwise normal males. Note=The disease is caused by mutations affecting the gene represented in this entry.

Similarity:
Belongs to the TGF-beta family.

SWISS:
P03971

Gene ID:
268

Database links:

Entrez Gene: 268 Human

Entrez Gene: 11705 Mouse

Entrez Gene: 25378 Rat

Omim: 600957 Human

SwissProt: P03971 Human

SwissProt: P27106 Mouse

SwissProt: P49000 Rat

Unigene: 112432 Human

Unigene: 19121 Rat



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