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BMP5 Rabbit pAb (bs-6614R)  
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50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
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產品編號 bs-6614R
英文名稱 BMP5 Rabbit pAb
中文名稱 骨形態發生蛋白5抗體
別    名 BMP 5; BMP-5; Bmp5; BMP5_HUMAN; Bone morphogenetic protein 5; MGC34244.  
Specific References  (1)     |     bs-6614R has been referenced in 1 publications.
[IF=2.24] Wu, Mei, et al. "Expression analysis of BMP2, BMP5, BMP10 in human colon tissues from Hirschsprung disease patients." Int J Clin Exp Pathol 7.2 (2014): 529-536.  IHC-P,WB ;  Human.  
研究領域 心血管  信號轉導  干細胞  生長因子和激素  細胞骨架  細胞外基質  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human,Mouse,Rat,Rabbit,Pig,Sheep,Chicken,Horse)
產品應用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 16 kDa
檢測分子量
細胞定位 分泌型蛋白 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human BMP5: 317-360/454 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 This gene encodes a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors. Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. These proteins are synthesized as prepropeptides, cleaved, and then processed into dimeric proteins. This protein may act as an important signaling molecule within the trabecular meshwork and optic nerve head, and may play a potential role in glaucoma pathogenesis. This gene is differentially regulated during the formation of various tumors. [provided by RefSeq, Jul 2008].

Function:
Induces cartilage and bone formation.

Subunit:
Homodimer; disulfide-linked (By similarity).

Subcellular Location:
Secreted.

Tissue Specificity:
Expressed in the lung and liver.

Similarity:
Belongs to the TGF-beta family.

SWISS:
P22003

Gene ID:
653

Database links:

Entrez Gene: 653 Human

Omim: 112265 Human

SwissProt: P22003 Human

Unigene: 296648 Human



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